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Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

✍ Scribed by Paul Edison; Hilary A. Archer; Alexander Gerhard; Rainer Hinz; Nicola Pavese; Federico E. Turkheimer; Alexander Hammers; Yen Fong Tai; Nick Fox; Angus Kennedy; Martin Rossor; David J. Brooks


Book ID
113812251
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
324 KB
Volume
32
Category
Article
ISSN
0969-9961

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## Abstract Positron emission tomography (PET) using [^11^C]PK 11195, a ligand for peripheral benzodiazepine receptor binding sites, offers the opportunity to image activated microglia in vivo. This tool may therefore be used to display the occurrence of microglial activation in the course of neuro