Microgels for Efficient Protein Purification
β Scribed by Boaz Mizrahi; Silvia Irusta; Marshall McKenna; Cristina Stefanescu; Liron Yedidsion; MyatNoeZin Myint; Robert Langer; Daniel S. Kohane
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 706 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0935-9648
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## Synopsis Salt-promoted adsorption of proteins occurs on hydrophobic gels, on immobilized metal ions e.g., Znz+, C g + , Ni2+, Cu2+, and on newly described absorbents provisionally called "thiophilic gels." The latter gels are characterized by the ligand structure -SO,-CH,-CH,-S-R. In a simple
## Abstract Membrane systems are used throughout the downstream purification in the commercial production of high value therapeutic proteins. Over the last two decades, new membranes, modules, and systems have been developed specifically to meet the requirements of the biotechnology industry. These