Microdialysis as a tool for in vivo investigation of glutamate transport capacity in rat brain
β Scribed by Torben Bruhn; Thomas Christensen; Nils H. Diemer
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 584 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0165-0270
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
It is widely believed that expression of the vesicular glutamate transporter genes VGLUT1 and VGLUT2 is restricted to glutamatergic neurons and that the two transporters segregate in different sets of neurons. Using single-cell multiplex RT-PCR (sc-RT-mPCR), we show that VGLUT1 and VGLUT2 mRNAs were
Brain extracellular fluid (ECF) concentration of YM992, a novel antidepressant, was determined using brain microdialysis to investigate the high partition of this drug to the brain after systemic administration to rats. Plasma, cerebrospinal fluid (CSF), ECF and brain concentrations were determined