Microchip Zone Electrophoresis for High-Throughput Analysis of Monoclonal Antibody Charge Variants
β Scribed by Wheeler, Tobias D.; Sun, Jing Lucy; Pleiner, Sina; Geier, Holger; Dobberthien, Philine; Studts, Joey; Singh, Rajendra; Fathollahi, Bahram
- Book ID
- 121823181
- Publisher
- American Chemical Society
- Year
- 2014
- Tongue
- English
- Weight
- 563 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0003-2700
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π SIMILAR VOLUMES
## Abstract A capillary zone electrophoresis (CZE) method was developed for the rapid analysis of charge heterogeneity of immunoglobulin G (IgG) monoclonal antibodies (mAbs). The separation was carried out in a short, dynamically coated fusedβsilica capillary. A number of separation parameters were
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