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Microbiological transformation of 1,2-diphenyl-3,5 dioxo-4-n-butyl pyrazolidine (phenylbutazone)

✍ Scribed by J. Favero; F. Winternitz

Book ID
113006280
Publisher
Springer-Verlag
Year
1980
Tongue
English
Weight
720 KB
Volume
5
Category
Article
ISSN
0378-7966

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Synthesis of 3 or 5[14C] 4-butyl-1, 2-di
Synthesis of 3 or 5[14C] 4-butyl-1, 2-diphenyl-3, 5-pyrazolidinedione (phenylbutazone)
✍ S. Stavchansky; H. B. Kostenbauder 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 French ⚖ 136 KB

## Abstract The condensation of 1 or 3 [^14^C] n‐butylmalonate diethyl ester (III) with hydrazobenzene (IV) yields up to 90 per cent of 3 or 5 [^14^C] 4‐butyl‐1, 2‐diphenyl‐3, 5‐pyrazolidinedione, if n‐butyl alcohol is used as a solvent and the corresponding sodium alcoholate as a condensing agent