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Microbial Transformations of Two Lupane-Type Triterpenes and Anti-Tumor-Promoting Effects of the Transformation Products

✍ Scribed by Akihisa, Toshihiro; Takamine, Yoshio; Yoshizumi, Kazuo; Tokuda, Harukuni; Kimura, Yumiko; Ukiya, Motohiko; Nakahara, Toro; Yokochi, Toshihiro; Ichiishi, Eiichiro; Nishino, Hoyoku


Book ID
121428345
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
77 KB
Volume
65
Category
Article
ISSN
0163-3864

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Induction of DNA synthesis by the tumor promoter tetradecanoyl phorbol acetate (TPA) was studied in aline of cultured rat fibroblasts (Rat-1) and their Rous sarcoma virus-transformed derivative (Rat-l(RSV)). Following serum deprivation for 54 h t o achieve quiescence, semiconservative DNA replicatio