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Michael addition of indoles to electron deficient olefins in water catalysed by potassium bisulfate

โœ Scribed by R. Senthil Kumar


Book ID
102338201
Publisher
Journal of Heterocyclic Chemistry
Year
2006
Tongue
English
Weight
165 KB
Volume
43
Category
Article
ISSN
0022-152X

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The Ultra High Pressure Conjugate Addition of Indoles to Electron-Deficient Olefins. -Indole and methylindole are added to ฮฑ,ฮฒ-unsaturated ketones in the presence of catalytic amounts of Yb(OTf) 3 to afford 3-alkylated indoles. The more reactive and less sterically hindered electrophiles give good t