𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Micellar effects on the basic hydrolysis of indomethacin and related compounds

✍ Scribed by Antonio Cipiciani; Cynthia Ebert; Raimondo Germani; Paolo Linda; Mara Lovrecich; Fulvio Rubessa; Gianfranco Savelli


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
425 KB
Volume
74
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Kinetics and mechanism of the basic hydr
✍ Antonio Cipiciani; Cynthia Ebert; Paolo Linda; Fulvio Rubessa; Gianfranco Savell πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 English βš– 205 KB πŸ‘ 1 views

The kinetics of the hydrolysis of indomethacin and related compounds were studied in an alkaline medium at 25 degrees. The pseudo-first-order rate constants were evaluated from log absorbance versus time plots in the ultraviolet. These compounds showed a second-order rate constant at low concentrati

Micellar effects upon the basic hydrolys
✍ Angela Cuenca πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 473 KB

The effect of cationic and anionic surfactants on the reaction of Basic Blue 3 (2,7-bis(diethylamino)phenazoxonium chloride, 1) with hydroxide ion has been studied. Cetyltrimethylammonium bromide (CTAB), cetyl and tetradecyltrimethylammonium chloride (CTAC and MTAC) enhance the rate of basic hydroly

Effect of liposomes on the rate of alkal
✍ C. Matos; H. Chaimovich; J.L.F.C. Lima; I.M. Cuccovia; S. Reis πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 266 KB πŸ‘ 2 views

The anti-inflammatory, analgesic, and antipyretic drugs indomethacin (INDO) and acemetacin (ACE), extensively used for the treatment of diseases of degenerative or inflammatory character, exhibit marked gastric irritant action, have low water solubility at neutral pH, and decompose in alkali. Altern

Micellar medium effects on the hydrolysi
✍ MarΓ­a MuΓ±oz; Amalia RodrΓ­guez; MarΓ­a Del Mar Graciani; MarΓ­a Luisa MoyΓ‘ πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 139 KB πŸ‘ 1 views

## Abstract The spontaneous hydrolysis of phenyl chloroformate was studied in various anionic, nonionic, zwitterionic, and cationic aqueous micellar solutions, as well as in mixed anionic–nonionic micellar solutions. In all cases, an increase in the surfactant concentration results in a decrease in

Effect of sodium deoxycholate on the dis
✍ Shih-Yu Lee; Albert A. Belmonte πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 303 KB πŸ‘ 1 views

The effects of sodium deoxycholate on the dissolution of indomethacin metal complexes were investigated. At pH 7.2, the dissolution of copper-indomethacin was very slow, while the dissolution of zinc-indomethacin was higher but less than that of indomethacin. In the presence of 5 mg of sodium deoxyc