Mice help nail down gene for rare syndrome
β Scribed by John Travis
- Book ID
- 115060047
- Publisher
- Society for Science & the Public
- Year
- 1998
- Tongue
- English
- Weight
- 179 KB
- Volume
- 154
- Category
- Article
- ISSN
- 0036-8423
- DOI
- 10.2307/4010691
No coin nor oath required. For personal study only.
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Ts65Dn mice are a genetic model for Down syndrome. Both individuals with Down syndrome and Ts65Dn mice have reduced cerebellar volumes and the cerebellum is involved in motor learning. ConΒ―icting results have been reported on the motor learning abilities of Ts65Dn mice, which may be related to proce
Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of th