MHC restriction of antigen-specific chicken T cells
โ Scribed by O. Vainio; E. Eerola; M.J.H. Ratcliffe
- Book ID
- 119076493
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 47 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0145-305X
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Current models for T-cell recognition of foreign antigen depict the T-cell receptor as having a single antibody-like combining site which bindr a complex of MHC and antigen. An alternative hypothesis is presented here; it is proposed that the first domains of the MHC function as inverted V-like regi
## Abstract The development of highโthroughput protein microarrays for rapidly determining antigenโspecific Tโcell receptor repertoires of diverse Tโcell populations can enable comprehensive, broadโbased analyses of Tโcell responses. Promising applications include medical diagnostics, vaccine devel