The basic structures of MHC class I and class II molecules are now well established. Over the past twelve months structural data on MHC class I molecules have provided details of the peptide binding groove for a number of alleles and have elaborated the mechanisms that allow binding of a range of pe
✦ LIBER ✦
MHC class II molecular structure — permitted pairs?
✍ Scribed by R.I. Lechler
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 423 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0167-5699
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## Abstract Proteins of the Major Histocompatibility Complex (MHC) bind self and nonself peptide antigens or epitopes within the cell and present them at the cell surface for recognition by T cells. All T‐cell epitopes are MHC binders but not all MCH binders are T‐cell epitopes. The MHC class II pr
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