𝔖 Bobbio Scriptorium
✦   LIBER   ✦

MHC class II antigen processing: biology of invariant chain

✍ Scribed by Andrea J. Sant; Jim Miller

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
937 KB
Volume
6
Category
Article
ISSN
0952-7915

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✦ Synopsis

The invariant chain (Ii) has been shown to play a critical role in the assembly, intracellular transport and function of MHC class II molecules. Recent studies suggest that these distinct activities can in many cases be attributed to distinct isoforms of Ii or to specific regions within it. Thus, regulation of Ii synthesis, post-transcriptional events, and post-translational modification has the potential to dramatically modulate immune responses.

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