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Mg 2+ -Dependent Conformational Changes in the Hammerhead Ribozyme †

✍ Scribed by Menger, Marcus; Tuschl, Thomas; Eckstein, Fritz; Porschke, Dietmar


Book ID
127079657
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
374 KB
Volume
35
Category
Article
ISSN
0006-2960

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## Abstract **Background:** Hepatitis delta virus (HDV) ribozymes cleave RNA in the presence of divalent metal ions. We have previously elucidated the solution conformation of a minimized __trans__‐acting HDV ribozyme and obtained evidence by NMR study that an Mg^2+^ ion binds to a site close to th