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Temperature-dependent change in the rate-determining step in a reaction catalyzed by a hammerhead ribozyme

✍ Scribed by Yasuomi Takagi; Kazunari Taira


Book ID
115930585
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
338 KB
Volume
361
Category
Article
ISSN
0014-5793

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## Abstract A consecutive single‐route reaction is considered. When two (groups of) steps compete in controlling the overall reaction rate, there exists a general rule that the earlier step in the flow of the overall reaction tends to be rate‐determining with the increase of the reaction affinity.