Metronidazole–Flavonoid Derivatives as Anti-Helicobacter pylori Agents with Potent Inhibitory Activity against HPE-Induced Interleukin-8 Production by AGS Cells

Metronidazole–Deoxybenzoin Derivatives a

Metronidazole–Deoxybenzoin Derivatives as Anti-Helicobacter pylori Agents with Potent Inhibitory Activity against HPE-Induced Interleukin-8

✍ Yin Luo; Huan-Qiu Li; Yang Zhou; Zi-Lin Li; Tao Yan; Hai-Liang Zhu 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 273 KB

## Abstract __A series of new metronidazole–deoxybenzoin derivatives were synthesized and evaluated for their antimicrobial activity against__ Helicobacter pylori__. Highly selective anti‐__H. pylori __activity was also observed in synthesized compounds. Compound **34** exhibited the most potent ac