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Methylprednisolone versus prednisolone pharmacokinetics in relation to dose in adults

✍ Scribed by S. J. Szefler; W. F. Ebling; J. W. Georgitis; W. J. Jusko


Publisher
Springer
Year
1986
Tongue
English
Weight
873 KB
Volume
30
Category
Article
ISSN
0031-6970

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## Abstract It has been reported that urinary excretion of two metabolites of valproic acid (VPA), 4‐ene‐valproic acid (4‐VPA) and 2,4‐diene‐valproic acid (2,4‐VPA), increased exponentially with the administration of high doses of VPA, and this increased formation of toxic metabolites could be rela