Methylenetetrahydrofolate reductase polymorphisms and plasma homocysteine in levodopa-treated and non-treated Parkinson's disease patients
โ Scribed by Rey-Yue Yuan; Jau-Jiuan Sheu; Jia-Ming Yu; Chaur-Jong Hu; Ing-Jy Tseng; Chun-Sum Ho; Ching-Ying Yeh; Ya-Lin Hung; Tsuey-Ru Chiang
- Book ID
- 119303561
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 182 KB
- Volume
- 287
- Category
- Article
- ISSN
- 0022-510X
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๐ SIMILAR VOLUMES
## Abstract Homocysteine, cysteine, and cysteinylโglycine are all metabolically interrelated. Levodopa/decarboxylase inhibitor (LD/DCI) administration increases total homocysteine (tHcy) plasma levels. Objectives were to investigate associations between LD/DCI intake, concentrations of tHcy, cystei
## Abstract Dementia is a frequent nonโmotor feature of Parkinson's disease (PD). Elevated plasma homocysteine (Hcy) levels have been associated with both cognitive impairment and dementia. Increased Hcy levels have been observed in levodopaโtreated patients with PD. The objective of our study was
## Abstract Homocysteine (Hcy) is a risk factor for vascular diseases, cognitive impairment, and dementia. Elevated plasma concentrations of Hcy have been found recently in Parkinson's disease (PD) patients treated with levodopa, suggesting that levodopa is a cause of hyperhomocysteinemia (HHcy). T