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Methyl- and (Trifluoromethyl)alkene Peptide Isosteres: Synthesis and Evaluation of Their Potential as β-Turn Promoters and Peptide Mimetics

✍ Scribed by Wipf, Peter; Henninger, Todd C.; Geib, Steven J.


Book ID
115504112
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
157 KB
Volume
63
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Methyl- and (Triflu
✍ P. WIPF; T. C. HENNINGER; S. J. GEIB 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 39 KB 👁 1 views

Methyl-and (Trifluoromethyl) alkene Peptide Isosteres: Synthesis and Evaluation of Their Potential as β-Turn Promoters and Peptide Mimetics. -Enantioselective synthetic approaches toward L-Ala-D-Ala (or enantiomeric) dipeptide isosteres are presented, including for the first time the preparation o