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Methotrexate pharmacogenetics: The first step toward individualized therapy in rheumatoid arthritis

✍ Scribed by Prabha Ranganathan; Howard L. McLeod


Book ID
101646816
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
105 KB
Volume
54
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To develop a clinical pharmacogenetic model to predict the efficacy of methotrexate (MTX) in rheumatoid arthritis (RA). ## Methods Two hundred five patients with newly diagnosed RA and active disease were treated with MTX (initiated at a dosage of 7.5 mg/week and increas