Use of methotrexate in refractory Crohn'
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Shahida Din; Anna Dahele; Janice Fennel; Sue Aitken; Alan G. Shand; Ian D.R. Arn
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Article
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2008
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John Wiley and Sons
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English
β 187 KB
π 2 views
## Background: In the two benchmark controlled trials in Crohn's disease (CD) supporting its use, methotrexate (MTX) was used as the immunosuppressant of choice in immunomodulatory-naive patients. However, in daily clinical practice MTX is used generally after thiopurine analogs have failed. ## Me