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Methods of analysis for 2-dodecylcyclobutanone and studies to support its role as a unique marker of food irradiation

✍ Scribed by Driffield, M.; Speck, D.; Lloyd, A.S.; Parmar, M.; Crews, C.; Castle, L.; Thomas, C.

Book ID: 123093701
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 474 KB
Volume: 146
Category: Article
ISSN: 0308-8146
DOI: 10.1016/j.foodchem.2013.09.046

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Acute and Chronic Toxicity of Veratrum V

Acute and Chronic Toxicity of Veratrum Viride††The Veratrum viride studied was the whole-powdered drug marketed by Irwin, Neisler & Co. under the name, Vertavis. The work reported herein was supported by a grant from this firm. The batch of powder used in these experiments was stated by the manufacturer to have been assayed biologically by the Craw method on Daphnia magna. One Craw unit of the material studied was stated to be 15.6mg. With regard to this assay, Mr. R. O. Craw has been so kind as to allow us to publish a brief explanation: A reference lot of Yerolrum oirid; powder was set-aside as a standard and a 10% w/v aqueous extract was made of this powder. The average median length of life in 50 assays of 1000 daphnia on immersion in the solution was determined to be 2.22 hours. The daphnia were considered dead when the heart was found to be in systolic standstill on microscopic examination. Succeeding lots of powder were assayed and their potency determined by relating the median length of life of daphnia to 2.22 hours, which is one unit. Twenty assays of 10 animals each were used on each lot of powder.‡‡The authors wish to thank Dr. J. F. A.,McManus of the Department of Pathology for a pathologic report on the tissues, and Mr. James Thomas and Mrs. Bobby E. Teague for technical assistance.

✍ Perdue, Adoline S. ;Bell, Frances ;Starnes, W.R. ;Hitchcock, Philip ;Teague, R.S 📂 Article 📅 1950 🏛 Elsevier ⚖ 346 KB 👁 2 views

Bio-Assays for Oxidative Stress Status |

Bio-Assays for Oxidative Stress Status || IN VIVO TOTAL ANTIOXIDANT CAPACITY: COMPARISON OF DIFFERENT ANALYTICAL METHODS11Mention of a trade name, proprietary product, or specific equipment does not constitute a guarantee by the U.S. Department of Agriculture and does not imply its approval to the exclusion of other products that may be suitable.Address correspondence to: R. L. Prior, Ph.D., USDA, ARS, HNRCA, 711 Washington St., Boston, MA 02111, USA; Tel: (617) 556–3311; Fax: (617) 556-3222; E-Mail: [email protected]. Ronald Prior is a Nutritionist and Laboratory Chief of the Phytochemical Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University, Boston, MA. Dr. Prior received his B.S. degree with honors from the University of Nebraska and he received his Ph.D. in Nutrition and Biochemistry from Cornell University in 1972. Dr. Prior has worked with the USDA for more than 20 years.During the past 12 years at the HNRCA, he has been Scientific Program Officer and has directed research activities dealing with the role of flavonoid and other phenolic food components on antioxidant status, their metabolism, and relationships to diseases of aging.Guohua Cao, M.D., Ph.D., is currently a Scientist II at HNRCA. Dr. Cao studied medicine in Nantong Medical College in 1979 and at Nanjing Medical University in 1984. He obtained his Ph.D. in nutritional biochemistry from Beijing Medical University in 1990. Dr. Cao came to the United States in 1991 and worked at NIH where he was instrumental in developing the ORAC method.

✍ PRIOR, RONALD L. 📂 Article 📅 2001 🏛 Elsevier 🌐 English ⚖ 986 KB

This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, *Free Radical Biology & Medicine*. The papers in this Forum (or Symposium-in-print) spanned seven issues of the journal