[Methods in Molecular Biology] Mitochondrial DNA || Establishment of Human Cell Lines Lacking Mitochondrial DNA
โ Scribed by Stuart, Jeffrey A.
- Book ID
- 111642441
- Publisher
- Humana Press
- Year
- 2009
- Weight
- 252 KB
- Category
- Article
- ISBN
- 1597455210
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๐ SIMILAR VOLUMES
Mitochondrial disorders are complex and heterogeneous diseases that may be caused by molecular defects in either the nuclear or mitochondrial genome. The biosynthesis and maintenance of the integrity of the mitochondrial genome is solely dependent on a number of nuclear proteins. Defects in these nu
The maintenance of mtDNA has been examined in human intraspecific hybrid cells constructed from the fusion of HEB7A, a HeLa tumor cell line carrying the mitochondrially coded chloramphenical (CAP) resistance mutation, and GM 2291, a limited lifespan human diploid fibroblast which is CAP sensitive. T