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Methods for indole alkaloid synthesis:Reactions of n-arylsulfonylenamines with electrophiles. An expeditious synthesis of (±)-eburnamonine.

✍ Scribed by Philip Magnus; Paul Pappalardo; Ian Southwell


Book ID
108371738
Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
459 KB
Volume
42
Category
Article
ISSN
0040-4020

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Highly diastereoselective construction of the chiral building blocks, with an allylic quaternary carbon stereogenic center, for the synthesis of indole alkaloids has been accomplished by employing a 1,4-chirality transfer via the intramolecular Heck reaction.