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Methodology of long-term culture of human hemopoietic cells

✍ Scribed by Connie J. Eaves; Johanne D. Cashman; Allen C. Eaves


Publisher
Springer
Year
1991
Tongue
English
Weight
894 KB
Volume
13
Category
Article
ISSN
1573-0603

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## Abstract Human embryonic stem cells (hESCs) during long‐term culture acquire chromosomal changes similar to those occurring in tumorigenesis. This was raised concerns about the progression from hESCs to malignant cells. This study aimed to investigate the changes in chromosomes, cell phenotype,