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Method for the Solid-Phase Parallel Synthesis of a 6-Alkylamino-2-(functionalized-aminomethyl)-2H-1-benzopyran Library

✍ Scribed by Hwang, Jong Yeon; Choi, Hyung-Sub; Seo, Jin-soo; La, Hyun-Ju; Yoo, Sung-eun; Gong, Young-Dae


Book ID
111954676
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
288 KB
Volume
8
Category
Article
ISSN
1520-4766

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The use of pentafluoronitrobenzene as a scaffold for solid-phase synthesis of 2,4,6-substituted-3,5-difluoronitrobenzenes is described. The scaffold is amenable to the synthesis of structurally diverse combinatorial libraries. Primary and secondary amines can be introduced to the scaffold via three