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Method for evaluating metabolic functions of drugs in bioartificial liver

โœ Scribed by Yueng Guen Park; Hiroo Iwata; Seiji Satoh; Takehiko Uesugi; Hwa-Won Ryu


Publisher
The Korean Society for Biotechnology and Bioengineering
Year
2003
Tongue
English
Weight
178 KB
Volume
8
Category
Article
ISSN
1226-8372

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โœ William R. Gillespie; Haiyung Cheng ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 530 KB

A general multidimensional deconvolution method is developed primarily for application to the bioavailability assessment of drugs with reversible metabolism. The proposed approach involves fitting continuous functions to the experimental data and then applying a numerical deconvolution algorithm to