𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Evaluation of SupermixTM as an in vitro model of human liver microsomal drug metabolism

✍ Scribed by Karthik Venkatakrishnan; Lisa L. von Moltke; David J. Greenblatt


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
100 KB
Volume
23
Category
Article
ISSN
0142-2782

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Stereoselective metabolism of tazofelone
✍ Michael P. Clay; Brenda R. Hanssen; Sekhar S. Surapaneni; Terry D. Lindstrom πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 181 KB πŸ‘ 1 views

Incubation of (R)-tazofelone and (S)-tazofelone in rat, dog, and human liver microsomes demonstrated that the (R)-tazofelone enantiomer was more rapidly metabolized, with two diastereomeric sulfoxides as the major metabolites formed in all three species. The two diasteresomers epimerized at physiolo

Validation of excised bovine nasal mucos
✍ M. Christiane Schmidt; Daniel Simmen; Monika Hilbe; Peter Boderke; GΓΌnter Ditzin πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 360 KB πŸ‘ 1 views

The present work aims at the validation of excised bovine nasal mucosa as an in vitro model to address transport and metabolism pathways relative to the nasal mucosal uptake of therapeutic peptides. Preservation of the viability of the excised tissue in the course of in vitro studies of up to 3 h wa

An evaluation of the use of defeat-induc
✍ Lynne P. Marrow; Paul F. Brain πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 32 KB πŸ‘ 2 views

Social defeat by Tryon Maze Dull rats, resulting in loss of rank of a previously dominant rat, has recently been advanced as a model of loss of self-esteem and depression in humans. However, before loss of rank in animals can be assessed as a model of human depression, certain requirements must be f