𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Method for determination of first-pass metabolism in human skin

✍ Scribed by Avraham Yacobi; Robert A. Baughman; Donna B. Cosulich; Gabriela Nicolau

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
265 KB
Volume
73
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

A method for calculating the mean absorp
A method for calculating the mean absorption time of drugs undergoing reversible and first-pass metabolism
✍ Haiyung Cheng; Linyee Shum πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 412 KB πŸ‘ 2 views

A method has been derived for calculating the mean absorption time of an oral drug and its interconversion metabolite which is generated from the drug systemically and presystemically. The method evolves from the convolution integral and requires plasma AUC and AUMC values after separate intravenous

GLC method for quantitative determinatio
GLC method for quantitative determination of amitriptyline in human plasma
✍ Howard B. Hucker; Susan C. Stauffer πŸ“‚ Article πŸ“… 1974 πŸ› John Wiley and Sons 🌐 English βš– 216 KB πŸ‘ 1 views

A GLC method was developed for the measurement of steady-state levels of amitriptyline and nortriptyline in human plasma after therapeutic doses of amitriptyline. The drugs were extracted from alkalinized samples with heptane-3% isoamyl alcohol and back-extracted into 0.1 N HCI. After subsequent ext