Methanolysis of 2-Phenylfuro[3,4-d] pyrimidine-5,7-dione
โ Scribed by Thomas J. Schuian
- Book ID
- 112124107
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1977
- Tongue
- English
- Weight
- 91 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Pyrazoloโ[3,4โ__d__]pyrimidineโ4,6โdiones **5** and pyrazolo[4,3โ__d__]pyrimidineโ5,7โdiones **7** were synthesized by Curtius rearrangement of pyrazolic monoโesters **2** and **3** followed by heteroโcyclization __via__ the ureas derivatives **4** and **6** under alkaline conditions.
Novel 2,3-substituted-2,4-dihydro-pyrazolo[4,3-d] pyrimidine-5,7-diones were successfully synthesized with moderate to good yields using a new synthetic approach. The structures of the regio-isomers in this series were determined by single crystal X-ray analysis and NMR spectra.