Methanol potentiation of carbon tetrachloride hepatotoxicity: The central role of cytochrome P450
β Scribed by John W. Allis; Barbara L. Brown; Jane Ellen Simmons; Gary E. Hatch; Anthony McDonald; Dennis E. House
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 987 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0300-483X
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## Abstract Cytochrome __b__~5~, a 17βkDa hemeprotein associated primarily with the endoplasmic reticulum of eukaryotic cells, has long been known to augment some cytochrome P450 monooxygenase reactions, but the mechanism of stimulation has remained controversial. Studies in recent years have clari