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Metformin reduces the stimulatory effect of obesity on in vivo Walker-256 tumor development and increases the area of tumor necrosis

✍ Scribed by Eveline Aparecida Isquierdo Fonseca; Maria Aparecida de Oliveira; Núbia de Souza Lobato; Eliana Hiromi Akamine; Alison Colquhoun; Maria Helena Catelli de Carvalho; Szulim Ber Zyngier; Zuleica Bruno Fortes


Book ID
116719974
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
936 KB
Volume
88
Category
Article
ISSN
0024-3205

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## Background: Previous studies have shown an upregulation of matrix metalloproteinases (mmps) in intestinal tissue of patients with inflammatory bowel disease (ibd) and significant clinical improvement after administration of the anti-tnf-a antibody infliximab. the aims of our study were to determ