Metastatic sarcomas: Chemotherapy with adriamycin, cyclophosphamide, and methotrexate alternating with actinomycin D, DTIC, and vincristine
β Scribed by Cary A. Presant; Stanley Lowenbraun; Alfred A. Bartolucci; Richard V. Smalley
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 704 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0008-543X
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Intensive chemotherapy with high-dose cyclophosphamide and adriamycin with DTIC maintenance was given to 12 patients with metastatic soft tissue sarcomas. A partial response rate of 25% was seen; this is no better than can be achieved with single-agent therapy. Because of substantial toxicity withou
Twenty-nine patients with metastatic breast cancer were treated with fluorouracil, adriamycin, cyclophosphamide (FAC), and methotrexate (MTX), with or without leukovorin rescue. Of 24 evaluable patients, one achieved a complete remission and 17 had partial responses. The overall objective response r