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High-dose cyclophosphamide and adriamycin with DTIC maintenance for metastatic soft tissue sarcomas

✍ Scribed by Gerald Clamon; Christine Sinkey; Peter Jochimsen

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 222 KB
Volume: 23
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930230413

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✦ Synopsis

Intensive chemotherapy with high-dose cyclophosphamide and adriamycin with DTIC maintenance was given to 12 patients with metastatic soft tissue sarcomas. A partial response rate of 25% was seen; this is no better than can be achieved with single-agent therapy. Because of substantial toxicity without improved efficacy, the trial of high dose therapy was halted.

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