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Metastatic melanoma imaging with an 111In-labeled lactam bridge-cyclized α-melanocyte-stimulating hormone peptide

✍ Scribed by Haixun Guo; Nalini Shenoy; Benjamin M. Gershman; Jianquan Yang; Larry A. Sklar; Yubin Miao

Book ID: 116799306
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 570 KB
Volume: 36
Category: Article
ISSN: 0969-8051
DOI: 10.1016/j.nucmedbio.2009.01.003

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## BACKGROUND. Previous studies have shown that the compact structure of a rhenium-cyclized ␣-melanocyte-stimulating hormone peptide analog, [Cys 3,4,10 ,D- Phe 7 ]␣-MSH 3-13 , or Re-CCMSH, significantly enhanced its in vivo tumor uptake and retention. In this study, the metal chelate 1,4,7,10-tet