Metallothionein induction and metal homeostasis in rainbow trout hepatocytes exposed to mercury
✍ Scribed by Gagné, François; Marion, Michel; Denizeau, Francine
- Book ID
- 123279716
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 532 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0378-4274
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In the present experiment, metabolically active primary cultures of rainbow trout hepatocytes were utilized to study the inducibility of metallothionein after cortisol treatment. Glucocorticoid induction of metallothionein has previously only been demonstrated in mammalian systems. We now demonstrat
Primary cultures of rainbow trout hepatocyte are proposed as an alternative to the rainbow trout bioassay for evaluating mortality, hepatic metallothionein and cytochrome P4501A activity inductions, and hepatic DNA damage with industrial effluents. The validation study sought to assess the ( ) perfo