๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Metallation of rigid 2-aryl-1,3-dioxanes

โœ Scribed by Arthur L. Campbell; Ish Kumar Khanna


Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
203 KB
Volume
27
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis


Regioselective metallation and alkylation/acylation of 2-aryl-1,3-dioxanes was achieved in high yield.


๐Ÿ“œ SIMILAR VOLUMES


Stereoelectronic effects on metallation
โœ A.I. Meyers; Arthur L. Campbell; Anthony G. Abatjoglou; Ernest L. Eliel ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 205 KB

Metallation of the acetal (H-2) proton in 1,3-dioxolanes, 1,3-dioxanes and open chain acetals is possible only if the proton can occupy an "equatorial-like" conformation.

Structure of 5-aryl-5-nitro-2-R-1,3-diox
โœ M. A. Khusainov; I. T. Kirillov; D. M. Kukovitskii; A. E. Obodovskaya; Z. A. Sta ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› SP MAIK Nauka/Interperiodica ๐ŸŒ English โš– 320 KB
Study on the atropisomerism of some new
โœ Ion Grosu; Gerard Plรฉ; Sorin Mager; Eugen Mesaros; Anca Dulau; Csaba Gego ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 402 KB

The synthesis and the stereocbemistry of a new class of compounds showing atropisomerism, the 1,3-dioxane derivatives bearing disymmetric axial aryl groups in position 2 of the 1,3-dioxane ring are reported.

The contrasting comformational behaviour
โœ Michael J. Cook; Khalida Nasri; Sunil M. Vather ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 123 KB

tie chair + chair equilibrium of 5-aryl-5-methyl-1,3-dioxanes, unlike that of 1-aryl-I-methylcyclohexanes, is remarkably sensitive to the nature of substituents on the aromatic ring. An interaction involving the the arcmatic group and the dioxane oxygen atoms or C-O bonds is proposed.