Structure of 5-aryl-5-nitro-2-R-1,3-dioxanes
β Scribed by M. A. Khusainov; I. T. Kirillov; D. M. Kukovitskii; A. E. Obodovskaya; Z. A. Starikova; R. S. Musavirov; V. V. Zorin; D. L. Rakhmankulov
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 1990
- Tongue
- English
- Weight
- 320 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0022-4766
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## Abstract (2__R__,4__S__,5__S__)β(+)β5β(2,2βDichloroacetamido)β4β(4βnitrophenyl)β2βarylβ1,3βdioxanes **3β8** were synthesized with high diastereoselectivity and good yields. The structures of acetals were determined and the configurations were confirmed by 2DβNMR (NOESY) and Xβray crystallographi
tie chair + chair equilibrium of 5-aryl-5-methyl-1,3-dioxanes, unlike that of 1-aryl-I-methylcyclohexanes, is remarkably sensitive to the nature of substituents on the aromatic ring. An interaction involving the the arcmatic group and the dioxane oxygen atoms or C-O bonds is proposed.