Metal-free synthesis of aryl esters by coupling aryl carboxylic acids and aryl boronic acids
✍ Scribed by Ruso, Jayaraman Sembian; Rajendiran, Nagappan; Kumaran, Rajendran Senthil
- Book ID
- 122945563
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- French
- Weight
- 618 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Aryl bromides and iodides can be coupled with phenylboronic acid in good yields using NiCl 2 •6H 2 O as a catalyst precursor. This nickel complex is cheap, widely available and can be used without any auxiliary ligand or reducing agent.
Palladium(II) acetate and N, N-bis-(2,6-diisopropylphenyl)dihydroimidazolium chloride (2 mol%) were used to catalyze the carbonylative coupling of aryl diazonium tetrafluoroborate salts and aryl boronic acids to form aryl ketones. Optimal conditions include carbon monoxide (1 atm) in 1,4-dioxane at