Suzuki cross-coupling of aryl halides with aryl boronic acids catalyzed by phosphine-free NiCl2·6H2O

✍ Scribed by Danilo Zim; Adriano L. Monteiro

• Book ID: 104251134
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 259 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)00716-5

✦ Synopsis

Aryl bromides and iodides can be coupled with phenylboronic acid in good yields using NiCl 2 •6H 2 O as a catalyst precursor. This nickel complex is cheap, widely available and can be used without any auxiliary ligand or reducing agent.