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Metal-Free Direct Asymmetric Aminoxylation of Aldehydes Catalyzed by a Binaphthyl-Based Chiral Amine

✍ Scribed by Taichi Kano; Haruka Mii; Keiji Maruoka


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
335 KB
Volume
49
Category
Article
ISSN
0044-8249

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## Abstract Nitroso compounds have two reactive nitrogen and oxygen atoms. It is interesting and important to perform a nitrogen or oxygen selective reaction with interesting substrates. These atom specific reactions are crucial to specifically synthesis of specific compounds. An enantioselective _

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## Abstract The bromination of aldehydes (I) in the presence of a chiral binaphthyl catalyst (BNS) followed by reduction of the intermediate α‐bromoaldehyde gives rise to bromohydrins (II) with high enantioselectivity.