Metal-free catalytic vicinal diamination of alkenes

✍ Scribed by Muñiz, Kilian

• Book ID: 120387808
• Publisher: International Union of Pure and Applied Chemistry
• Year: 2013
• Tongue: English
• Weight: 475 KB
• Volume: 85
• Category: Article
• ISSN: 0033-4545
• DOI: 10.1351/PAC-CON-12-10-23

✦ Synopsis

The development of an intramolecular vicinal diamination protocol using metal-free conditions is discussed. The reaction uses a bromide source to generate a Br(I) catalyst in situ from a benign terminal oxidant such as sodium chlorite. The reaction is of great scope and surpasses the transition-metal catalyses developed so far for these types of reactions.