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Metal-Free Catalytic Nucleophilic Substitution of Propargylic Alcohols.

✍ Scribed by Roberto Sanz; Alberto Martinez; Julia M. Alvarez-Gutierrez; Felix Rodriguez


Publisher
John Wiley and Sons
Year
2006
Weight
28 KB
Volume
37
Category
Article
ISSN
0931-7597

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Metal-Free Catalytic Nucleophilic Substi
✍ Roberto Sanz; Alberto MartΓ­nez; Julia M. Álvarez-GutiΓ©rrez; FΓ©lix RodrΓ­guez πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 90 KB πŸ‘ 1 views

## Abstract Organic acids such as PTS efficiently catalyze direct nucleophilic substitutions of the hydroxy groups of propargylic alcohols with a large variety of carbon‐ and heteroatom‐centered nucleophiles. Reactions can be conducted under mild conditions and in air without the need for dried sol