Metal-Free Catalytic Nucleophilic Substi
β
Roberto Sanz; Alberto MartΓnez; Julia M. Γlvarez-GutiΓ©rrez; FΓ©lix RodrΓguez
π
Article
π
2006
π
John Wiley and Sons
π
English
β 90 KB
π 1 views
## Abstract Organic acids such as PTS efficiently catalyze direct nucleophilic substitutions of the hydroxy groups of propargylic alcohols with a large variety of carbonβ and heteroatomβcentered nucleophiles. Reactions can be conducted under mild conditions and in air without the need for dried sol