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Metal-Catalyzed Derivatization of Cα-Tetrasubstituted Amino Acids and Their Use in the Synthesis of Cyclic Peptides

✍ Scribed by Andreas Grauer; Andreas Späth; Dawei Ma; Burkhard König

Book ID
112005715
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
314 KB
Volume
4
Category
Article
ISSN
1861-4728

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✍ Prantik Maity; Burkhard König 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 589 KB

## Abstract C^α^‐Tetrasubstituted α‐amino acids are widely used to design and prepare peptides and peptide mimics with constrained conformations. Subcategories of these compounds are cyclic C^α^‐tetrasubstituted α‐amino acids, in which both α‐substituents are covalently connected. This survey prese