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ChemInform Abstract: Enantio- and Diastereoselective Syntheses of Cyclic Cα-Tetrasubstituted α-Amino Acids and Their Use to Induce Stable Conformations in Short Peptides

✍ Scribed by Prantik Maity; Burkhard Koenig

Publisher
John Wiley and Sons
Year
2008
Weight
16 KB
Volume
39
Category
Article
ISSN
0931-7597

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Enantio- and diastereoselective synthese
Enantio- and diastereoselective syntheses of cyclic Cα-tetrasubstituted α-amino acids and their use to induce stable conformations in short peptides
✍ Prantik Maity; Burkhard König 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 589 KB

## Abstract C^α^‐Tetrasubstituted α‐amino acids are widely used to design and prepare peptides and peptide mimics with constrained conformations. Subcategories of these compounds are cyclic C^α^‐tetrasubstituted α‐amino acids, in which both α‐substituents are covalently connected. This survey prese