✦ LIBER ✦

Metabotropic glutamate receptor 4 (mGlu 4 )-positive allosteric modulators for the treatment of Parkinson's disease: historical perspective and review of the patent literature

✍ Scribed by Lindsley, Craig W; Hopkins, Corey R

Book ID: 125537225
Publisher: Informa plc
Year: 2012
Tongue: English
Weight: 783 KB
Volume: 22
Category: Article
ISSN: 1354-3776
DOI: 10.1517/13543776.2012.679437

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

P2.118 Allosteric modulation of group II

P2.118 Allosteric modulation of group III metabotropic glutamate receptor 4: a potential neuroprotective approach for the treatment of Parkinson's disease

✍ M. Betts; M. O'Neill; S. Mitchell; S. Duty 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 58 KB

Metabotropic glutamate receptor subtype

Metabotropic glutamate receptor subtype 4 selectively modulates both glutamate and GABA transmission in the striatum: implications for Parkinson’s disease treatment

✍ Dario Cuomo; Giuseppina Martella; Emanuela Barabino; Paola Platania; Daniela Vit 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 555 KB

P2.105 The development of positive allos

P2.105 The development of positive allosteric modulators of mGluR4 for the treatment of Parkinson's disease

✍ C. Niswender; C. Hopkins; C. Jones; A. Thompson; D. Engers; R. Williams; S. Zhou 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 68 KB

Targets and Emerging Therapies for Schiz

Targets and Emerging Therapies for Schizophrenia (Albert/Pharmacological Schizophrenia) || Metabotropic Glutamate 2/3 Receptor Agonists and Positive Allosteric Modulators of Metabotropic Glutamate Receptor 2 as Novel Agents for the Treatment of Schizophrenia

✍ Albert, Jeffrey S.; Wood, Michael W. 📂 Article 📅 2012 🏛 John Wiley & Sons, Inc. ⚖ 235 KB

Characterization of the Novel Positive A

Characterization of the Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 ADX88178 in Rodent Models of Neuropsychiatric Disorders

✍ Kalinichev, M.; Le Poul, E.; Bolea, C.; Girard, F.; Campo, B.; Fonsi, M.; Royer- 📂 Article 📅 2014 🏛 American Society for Pharmacology and Experimental 🌐 English ⚖ 893 KB

Discovery, Synthesis, and Structure–Acti

Discovery, Synthesis, and Structure–Activity Relationship Development of a Series of N -4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu 4 ) with Oral Efficacy in an Antiparkinsonian Animal Model

✍ Jones, Carrie K.; Engers, Darren W.; Thompson, Analisa D.; Field, Julie R.; Blob 📂 Article 📅 2011 🏛 American Chemical Society 🌐 English ⚖ 515 KB