Discovery, Synthesis, and Structure–Activity Relationship Development of a Series of N -4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu 4 ) with Oral Efficacy in an Antiparkinsonian Animal Model

✍ Scribed by Jones, Carrie K.; Engers, Darren W.; Thompson, Analisa D.; Field, Julie R.; Blobaum, Anna L.; Lindsley, Stacey R.; Zhou, Ya; Gogliotti, Rocco D.; Jadhav, Satyawan; Zamorano, Rocio; Bogenpohl, Jim; Smith, Yoland; Morrison, Ryan; Daniels, J. Scott; Weaver, C. David; Conn, P. Jeffrey; Lindsley, Craig W.; Niswender, Colleen M.; Hopkins, Corey R.

• Book ID: 121194208
• Publisher: American Chemical Society
• Year: 2011
• Tongue: English
• Weight: 515 KB
• Volume: 54
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm200956q