๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Metabolites of polycyclic aromatic hydrocarbons. II. Isomeric k-region phenols and methyl ethers of benz [a]anthracene

โœ Scribed by J.C. Wiley Jr.; C.S. Menon; D.L. Fischer; J.F. Engel

Book ID
104214910
Publisher
Elsevier Science
Year
1975
Tongue
French
Weight
196 KB
Volume
16
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

Polycyclic aromatic hydrocarbons (PAR) are metabolized primarily by enzymatic oxyganation which converts the hydrocarbons into polycyclic phenols, dihydrodiols, quinones, etc., and water-soluble conjugates.

1 These metabolites are thought to be formed via eporfde intermedi-2 ates, which readily isomerise to phenols. Metabolic studies of carcinogenic PAR require the availability of authentic samples of these metabolites, thus we have recently re-eramined the syntheses of some PAD K-region phenols via acid-catalyzed dehydration of their parent cis-dihydrodiols.

๐Ÿ“œ SIMILAR VOLUMES

Labeled metabolites of polycyclic aromat
Labeled metabolites of polycyclic aromatic hydrocarbons II. 4,5-dihydrobenzo[a]pyrene-4,5-epoxide-G-3H via cis 4,5-dihydrobenzo[a]pyrene-4,5-diol-G-3H
โœ Kenneth C. Kolwyck; W. P. Duncan; James F. Engel; James K. Selkirk ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 223 KB

Recent i n v e s t i g a t i o n s concerning t h e o x i d a t i v e metabolism of b e n z o k lpyrene (Be) have implicated various epoxides as intermediates [l].