Metabolites of demoxepam, a chlordiazepoxide metabolite, in man
โ Scribed by Lorton A. Schwartz; Edward Postma
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- English
- Weight
- 354 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0022-3549
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A derivatization procedure is described for the GLC determination of subnanogram amounts of chlordiazepoxide and nanogram amounts of N-desmethylchlordiazepoxide. Treatment with acetic anhydride at elevated temperature eliminates the highly polar and unstable nitrone group of these compounds by rearr