Rats trained on a restricted feeding (RF) schedule of 4 h/day were killed before (starved) and after (fed) the presentation of food to compare hepatic and brain tryptophan metabolism with feeding (FF) controls. The R F rats exhibited greater holo-tryptophan pyrrolase activity in the liver than FF co
Metabolites decrease the plasma clearance of isosorbide dinitrate in rats
โ Scribed by Steven C. Sutton; Ho-Leung Fung
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 235 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0142-2782
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A specific, accurate, precise, and reproducible High-performance liquid chromatographic-Ultraviolet (HPLC-W) method was developed for the simultaneous quantitation of BMS-181101 (I), a new antidepressant, and its putative metabolites, 6'-hydroxy (11) and 7'-hydroxy (111) of BMS-181101 in rat and mon