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Metabolism of tricycloquinazoline in mouse skin

โœ Scribed by R.W. Baldwin; M. Moore; J.Anna Nikolic; M.W. Partridge

Book ID
115769679
Publisher
Elsevier Science
Year
1968
Tongue
English
Weight
839 KB
Volume
17
Category
Article
ISSN
0006-2952

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Tricycloquinazoline carcinogenesis: Inte
Tricycloquinazoline carcinogenesis: Interaction of carcinogen with mouse skin proteins
โœ R. W. Baldwin; M. Moore; M. W. Partridge ๐Ÿ“‚ Article ๐Ÿ“… 1968 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 600 KB

Following topical application of tricycloquinazoline-14C (0.03 p M ) to mice, radioactivity was covalently bound to soluble and particulate skin proteins. The maxinium level of binding to soluble proteins (equivalent to 4 . 2 ~ p M TCQlmg) was reached after 24 hours and that to particulate proteins